The CNP Diet and Chronic Pain Research Category consolidates research exploring the interdependent relationship between dietary intake and pain. To view each original study on the open internet, click “Original.” To view the CNP-written abstract summary, click “CNP Summary.” While only some of the CNP-written abstract summaries are available below for free, all abstract summaries are available to CNP members through the CNP Library Membership.
This 2020 systematic review screened 20,316 articles from three large online scientific databases to analyse the current literature on the link between dietary patterns, the components of patients’ diet, and chronic musculoskeletal pain. Twelve eligible studies were included in this review, consisting of nine experimental and three observational studies. Seven out of nine experimental studies reported a pain-relieving effect of dietary changes. Proteins, fat, and sugar intake were all found to be associated with pain intensity and threshold, and also, inadequate consumption of calcium, folate, zinc, magnesium, and vitamin B6 was seen in sufferers of pain from chronic rheumatoid arthritis, whilst patients with fibromyalgia showed a lower intake of carbohydrates, proteins, lipids, vitamin A-E-K, folate, selenium, and zinc. Moreover, chronic pain severity was seen to be positively correlated to fat and sugar intake in osteoarthritis, and pain threshold was positively associated with protein intake in fibromyalgia. Elma et. al (2020) also believe plant-based diets might have pain-relieving effects on chronic musculoskeletal pain.
Irritable bowel syndrome and mental health comorbidity — approach to multidisciplinary management
Eating habits and the desire to eat healthier among patients with chronic pain: a registry-based study
CNP Research Summary can be found in the CNP Library Membership
Dietary fibre confers therapeutic effects in a preclinical model of Huntington’s disease.
Dietary wheat amylase trypsin inhibitors exacerbate CNS inflammation in experimental multiple sclerosis.
CNP Research Summary can be found in the CNP Library Membership
Association of higher Mediterranean diet adherence with lower prevalence of disability and symptom severity, depression, anxiety, stress, sleep quality, cognitive impairment, and physical inactivity in older adults with multiple sclerosis
CNP Research Summary can be found in the CNP Library Membership
A low-fat diet improves fatigue in multiple sclerosis: Results from a randomized controlled trial
Global trends in research of pain–gut-microbiota relationship and how nutrition can modulate this link
CNP Research Summary can be found in the CNP Library Membership
Elevated dietary ω-6 polyunsaturated fatty acids induce reversible peripheral nerve dysfunction that exacerbates comorbid pain conditions
High-fat diet causes mechanical allodynia in the absence of injury or diabetic pathology
Mediterranean diet and changes in frequency, severity, and localization of pain in older adults: The Seniors-ENRICA Cohorts
CNP Research Summary can be found in the CNP Library Membership
Relationship between diet and relative risk of pain in a cross-sectional analysis of the REGARDS longitudinal study
Participants with chronic pain do not perceive diet as a contributing factor to their pain: a survey-based study
Does diet play a role in reducing nociception related to inflammation and chronic pain?
CNP Research Summary can be found in the CNP Library Membership
Effects of nutritional interventions in the control of musculoskeletal pain: An integrative review
CNP Research Summary can be found in the CNP Library Membership
Poor diet quality is associated with self-reported knee pain in community-dwelling women aged 50 years and older
High-fat diet exacerbates postoperative pain and inflammation in a sex-dependent manner
CNP Research Summary can be found in the CNP Library Membership
Effect of anti-inflammatory diets on pain in rheumatoid arthritis: A systematic review and meta-analysis
Gluten-free diet reduces pain in women with myofascial pain in masticatory muscles: A preliminary randomized controlled trial
CNP Research Summary can be found in the CNP Library Membership
A systematic review and meta-analysis of nutrition interventions for chronic noncancer pain
Impact of diet on pain perception in women with endometriosis: A systematic review
CNP Research Summary can be found in the CNP Library Membership
Dietary patterns and interventions to alleviate chronic pain
CNP Research Summary can be found in the CNP Library Membership
Anti-inflammatory and anti-nociceptive effects of cocoa: A review on future perspectives in treatment of pain
CNP Research Summary can be found in the CNP Library Membership
Beneficial effect of Mediterranean diet on disease activity and cardiovascular risk in systemic lupus erythematosus patients: a cross-sectional study
Anti-inflammatory diet and inflammatory bowel disease: what clinicians and patients should know?
CNP Research Summary can be found in the CNP Library Membership
Inflammatory diseases and vitamin E-what do we know and where do we go?
The effects of antioxidant and anti-inflammatory capacity of diet on psoriasis and psoriatic arthritis phenotype: nutrition as therapeutic tool?
CNP Research Summary can be found in the CNP Library Membership
Ideal food pyramid for patients with rheumatoid arthritis: A narrative review
A bioavailable form of curcumin, in combination with vitamin-D- and omega-3-enriched diet, modifies disease onset and outcomes in a murine model of collagen-induced arthritis
CNP Research Summary can be found in the CNP Library Membership
A study protocol for a randomized controlled trial of an anti-inflammatory nutritional intervention in patients with fibromyalgia
The role of diet and nutrition in migraine triggers and treatment: A systematic literature review
CNP Research Summary can be found in the CNP Library Membership
A bidirectional view of Migraine and diet relationship
The effect of antioxidant and anti-inflammatory capacity of diet on psoriasis and psoriatic arthritis phenotype: Nutrition as therapeutic tool?
CNP Research Summary can be found in the CNP Library Membership
Dietary patterns and biomarkers of oxidative stress and inflammation: A systematic review of observational and intervention studies
Lifestyle and Mediterranean diet adherence in a cohort of Southern Italian patients with Multiple Sclerosis
CNP Research Summary can be found in the CNP Library Membership
Nutrition interventions in Rheumatoid Arthritis: The potential use of plant-based diets
Adherence to dietary guidelines is associated with better physical and mental quality of life: results from a cross-sectional survey among 728 Dutch MS patients
CNP Research Summary can be found in the CNP Library Membership
Blueberries improve pain, gait performance, and inflammation in individuals with symptomatic knee osteoarthritis
Chronic musculoskeletal pain and nutrition: Where are we and where are we heading?
CNP Research Summary can be found in the CNP Library Membership
Role of diet in diarrhea-predominant Irritable Bowel Syndrome
Gut-brain Axis: Role of lipids in the regulation of inflammation, pain and CNS diseases
CNP Research Summary can be found in the CNP Library Membership
Are probiotic treatments useful on fibromyalgia syndrome or chronic fatigue syndrome patients? A systematic review
CNP Research Summary can be found in the CNP Library Membership
Association of chronic spinal pain with diet quality
Nutritional intervention in chronic pain: an innovative way of targeting central nervous system sensitization?
CNP Research Summary can be found in the CNP Library Membership
Lifestyle and chronic pain across the lifespan: An inconvenient truth?
The relationship between dietary inflammatory index and psychosomatic complaints profiles: results from SEPAHAN cross-sectional study
CNP Research Summary can be found in the CNP Library Membership
Is healthier nutrition behaviour associated with better self-reported health and less health complaints? evidence from Turku, Finland
CNP Research Summary can be found in the CNP Library Membership
Nutritional status as a mediator of fatigue and its underlying mechanisms in older people
CNP Research Summary can be found in the CNP Library Membership
Pain regulation by gut microbiota: molecular mechanisms and therapeutic potential
CNP Research Summary can be found in the CNP Library Membership
Effect of vitamin D supplementation in chronic widespread pain: a systematic review and meta-analysis
The association between vitamin D concentration and pain: a systemic review and meta-analysis
CNP Research Summary can be found in the CNP Library Membership
Nutraceuticals and osteoarthritis pain
Cannabis and pain treatment—a review of the clinical utility and a practical approach in light of uncertainty
CNP Research Summary can be found in the CNP Library Membership
An experimental randomized study on the analgesic effects of pharmaceutical-grade cannabis in chronic pain patients with fibromyalgia
Physical activity, exercise and nutrition in rheumatism: Adjuvant treatment options for inflammatory-rheumatic diseases
CNP Research Summary can be found in the CNP Library Membership
A Review of scientific evidence for THC:CBD Oromucosal Spray (Nabiximols) in the Management of Chronic Pain
Cannabidiol modulates serotonergic transmission and reverses both allodynia and anxiety-like behavior in a model of neuropathic pain (animal)
CNP Research Summary can be found in the CNP Library Membership
Fibromyalgia and nutrition: therapeutic possibilities?
A low fermentable oligo-di-mono-saccharides and polyols (FODMAP) diet is a balanced therapy for Fibromyalgia with nutritional and symptomatic benefits
CNP Research Summary can be found in the CNP Library Membership
Chronic Fatigue Syndrome (CFS): Suggestions for a nutritional treatment in the therapeutic approach
Determining the association between Fibromyalgia, the gut microbiome and its biomarkers: a systematic review
CNP Research Summary can be found in the CNP Library Membership
The role of diet in the treatment of Fibromyalgia
CNP Research Summary can be found in the CNP Library Membership
Gut microbiome: pertinence in fibromyalgia
Combining pain therapy with lifestyle: the role of personalized nutrition and nutritional supplements according to the SIMPAR Feed Your Destiny Approach
CNP Research Summary can be found in the CNP Library Membership
Are probiotic treatments useful on Fibromyalgia Syndrome or Chronic Fatigue Syndrome Patients? A systematic review
Dietary Inflammatory Index scores are associated with pressure pain hypersensitivity in women with fibromyalgia
CNP Research Summary can be found in the CNP Library Membership
Altered microbiome composition in individuals with Fibromyalgia
CNP Research Summary can be found in the CNP Library Membership
Anti-inflammatory diets and fatigue
CNP Research Summary can be found in the CNP Library Membership
Food-derived natural compounds for pain relief in neuropathic pain
Integrative neuromuscular medicine: neuropathy and neuropathic pain: consider the alternatives
CNP Research Summary can be found in the CNP Library Membership
Visceral pain: gut microbiota, a new hope?
CNP Research Summary can be found in the CNP Library Membership
Do nutritional factors interact with chronic musculoskeletal pain? A systematic review