Micronutrients and Mental Health

The CNP Micronutrients and Mental Health Research Category consolidates research exploring the interdependent relationship between dietary intake and micronutrients. To view each original study on the open internet, click “Original.” To view the CNP-written abstract summary, click “CNP Summary.” While only some of the CNP-written abstract summaries are available below for free, all abstract summaries are available to CNP members through the CNP Library Membership.

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2023

Efficacy and safety of a vitamin-mineral intervention for symptoms of anxiety and depression in adults: A randomised placebo-controlled trial "NoMAD"

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CNP Research Summary can be found in the CNP Library Membership

2020

Vitamin B12 supplementation: Preventing onset and improving prognosis of depression

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2021

Zinc supplementation combined with antidepressant drugs for treatment of patients with depression: A systematic review and meta-analysis

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CNP Research Summary can be found in the CNP Library Membership

2022

Vitamin C supplementation promotes mental vitality in healthy young adults: Results from a cross-sectional analysis and a randomized, double-blind, placebo-controlled trial

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2021

Effect of vitamin D supplementation on outcomes in people with early psychosis: The DFEND randomized clinical trial

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CNP Research Summary can be found in the CNP Library Membership

2018

Superiority of magnesium and vitamin B6 over magnesium alone on severe stress in healthy adults with low magnesemia: A randomized, single-blind clinical trial

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2017

Role of magnesium supplementation in the treatment of depression: A randomized clinical trial

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CNP Research Summary can be found in the CNP Library Membership

2020

Risk factors for depression. New evidence on selenium deficiency and depressive

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2019

An observational preliminary study on the safety of long-term consumption of micronutrients for the treatment of psychiatric symptoms

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CNP Research Summary can be found in the CNP Library Membership

2015

A randomised trial of nutrient supplements to minimise psychological stress after a natural disaster

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2013

Assessment of dietary adequacy for important brain micronutrients in patients presenting to a traumatic brain injury clinic for evaluation

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CNP Research Summary can be found in the CNP Library Membership

2019

Influence of adjuvant Coenzyme Q10 on inflammatory and oxidative stress biomarkers in patients with bipolar disorders during the depressive episode

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2012

Effects of a multivitamin, mineral and herbal supplement on cognition and blood biomarkers in older men: a randomised, placebo-controlled trial

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CNP Research Summary can be found in the CNP Library Membership

2016

The effects of four-week multivitamin supplementation on mood in healthy older women: A randomized controlled trial

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2013

The effects of multivitamin supplementation on mood and general well-being in healthy young adults. A laboratory and at-home mobile phone assessment

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CNP Research Summary can be found in the CNP Library Membership

2013

Effects of vitamin and mineral supplementation on stress, mild psychiatric symptoms, and mood in nonclinical samples: A meta-analysis

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2011

The effect of multivitamin supplementation on mood and stress in healthy older men

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CNP Research Summary can be found in the CNP Library Membership

2010

Effects of high-dose B vitamin complex with vitamin C and minerals on subjective mood and performance in healthy males

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CNP Research Summary can be found in the CNP Library Membership

2020

Higher vitamin B 6 intake is associated with lower depression and anxiety risk in women but not in men: A large cross-sectional study

2020

Multinutrients for the treatment of psychiatric symptoms in clinical samples: A systematic review and meta-analysis of randomized controlled trials

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CNP Research Summary can be found in the CNP Library Membership

2020

Serum vitamin D concentrations are associated with depressive symptoms in men: The sixth Korea national health and nutrition examination survey 2014

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2019

Creatine for the treatment of depression

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CNP Research Summary can be found in the CNP Library Membership

2018

Alterations of serum macro-minerals and trace elements are associated with major depressive disorder: A case-control study

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2019

Evaluation of some trace elements and vitamins in Major Depressive Disorder patients: A case-control study

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CNP Research Summary can be found in the CNP Library Membership

2020

The role and the effect of magnesium in mental disorders: A systematic review

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2020

Evaluation of serum amino acids and non-enzymatic antioxidants in drug-naïve first-episode major depressive disorder

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CNP Research Summary can be found in the CNP Library Membership

2019

Vitamin B-6 and depressive symptomatology, over time, in older Latino adults

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2019

Greater circulating copper concentrations and copper/zinc ratios are associated with lower psychological distress, but not cognitive performance, in a sample of Australian older adults

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CNP Research Summary can be found in the CNP Library Membership

2021

Palmitoylethanolamide counteracts brain fog improving depressive-like behaviour in obese mice: Possible role of synaptic plasticity and neurogenesis

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2019

Is there a relationship between chocolate consumption and symptoms of depression? A cross-sectional survey of 13,626 US adults.

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CNP Research Summary can be found in the CNP Library Membership

2019

Association between tea consumption and depressive symptom among Chinese older adults

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2019

Association of dietary phytochemical index and mental health in women: A cross-sectional study

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CNP Research Summary can be found in the CNP Library Membership

2017

Effect of green tea phytochemicals on mood and cognition

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2019

The relationship between dietary vitamin K and depressive symptoms in late adulthood: A cross-sectional analysis from a large cohort study

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CNP Research Summary can be found in the CNP Library Membership

2016

Nutritional interventions in clinical depression

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2015

Essential elements in depression and anxiety. Part II

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CNP Research Summary can be found in the CNP Library Membership

2017

The role of elements in anxiety

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2019

Diet-induced hypothalamic dysfunction and metabolic disease, and the therapeutic potential of polyphenols

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CNP Research Summary can be found in the CNP Library Membership

2019

Dietary total antioxidant capacity as a preventive factor against depression in climacteric women

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2019

The efficacy and safety of nutrient supplements in the treatment of mental disorders: A meta-review of meta-analyses of randomized controlled trials

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CNP Research Summary can be found in the CNP Library Membership

2018

Zinc, magnesium, selenium and depression: A review of the evidence, potential mechanisms and implications

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2020

Higher vitamin B6 intake is associated with lower depression and anxiety risk in women but not in men: A large cross-sectional study

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CNP Research Summary can be found in the CNP Library Membership

2019

Association between lower intake of minerals and depressive symptoms among elderly Japanese women but not men: Findings from Shika study

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2020

Dietary creatine intake and depression risk among U.S. adults

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CNP Research Summary can be found in the CNP Library Membership

2019

A systematic review and meta-analysis of B vitamin supplementation on depressive symptoms, anxiety, and stress: effects on healthy and 'at-risk' individuals

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2018

The association between dietary intake of magnesium and psychiatric disorders among Iranian adults: A cross-sectional study

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CNP Research Summary can be found in the CNP Library Membership

2021

Nutrient and genetic biomarkers of nutraceutical treatment response in mood and psychotic disorders: A systematic review

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2018

The association between dietary intake of magnesium and psychiatric disorders among Iranian adults: A cross-sectional study

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CNP Research Summary can be found in the CNP Library Membership

2017

The impact of essential fatty acid, B vitamins, vitamin C, magnesium and zinc supplementation on stress levels in women: A systematic review

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2019

Low zinc, copper, and manganese intake is associated with depression and anxiety symptoms in the Japanese working population: Findings from the eating habit and well-being study

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CNP Research Summary can be found in the CNP Library Membership

2018

Database analysis of depression and anxiety in a community sample—response to a micronutrient intervention

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2018

Association of total zinc, iron, copper and selenium intakes with depression in the US adults

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