Satiety Cascade

The satiety cascade is a conceptual model describing the sequence of physiological and psychological signals that arise during and after eating and that progressively reduce the desire to eat, bringing a meal to an end and delaying the onset of the next one. The satiety cascade frames appetite control as a series of overlapping stages, beginning with sensory and cognitive responses to food (sight, smell, expectations), continuing through gastric and intestinal responses during digestion, and extending to post-absorptive metabolic and hormonal signals.

These integrated signals jointly determine satiation (meal termination and meal size) and post-meal satiety (how long hunger is suppressed before the next eating occasion).