The microbiota-gut-brain axis (MGBA) is a network of interconnected biological systems that facilitates bidirectional communication between the GIT and the brain (Morais et al., 2020). MGBA is essential for maintaining gastrointestinal and microbial ecosystem homeostasis and causing physiological changes in the brain that influence mood and behavior (Morais et al., 2020; Generoso et al., 2021),.