Antibiotic-induced microbiota depletion (AIMD) refers to the administration of one or more antibiotics that deplete the microbiota and disrupt the microbial balance, including richness and diversity. This can harm host health by increasing susceptibility to pathogen infection (Modi et al., 2014). This procedure is often used to investigate the role of gut microbiota in some pathological conditions (Patangia et al., 2022).