Afferent vagus nerves are the sensory neurons that carry information from various parts of the body organs (such as the gut) and transmit it to the brain (CNS) to cause some effect or action. It is responsible for relaying information about the state of the gut, including signals related to the presence of food, digestive activity, and change in the gut microbiota, to the brain, where they can influence the regulation of various physiological processes, such as heart rate, digestion, and immune function (Mikami et al., 2022).