Association of lifestyle and genetic risk with incidence of dementia
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The CNP Diet, Aging, and Neurodegeneration Research Category consolidates research exploring the interdependent relationship between dietary intake and aging and neurodegeneration. To view each original study on the open internet, click “Original.” To view the CNP-written abstract summary, click “CNP Summary.” While only some CNP-written abstract summaries are available below for free, all abstract summaries are available to CNP members through the CNP Library Membership.
Various epidemiological studies have explored the link between coffee or tea consumption and the likelihood of cognitive disorders, yet findings have been inconclusive. To further the understanding of this topic, Zhu et al. (2024) conducted a comprehensive review and meta-analysis to examine the impact of coffee, tea, and caffeine intake on cognitive disorder risk. The review searched PubMed, Embase, and Web of Science databases up to January 2022, gathering studies on dementia, Alzheimer's disease (AD), and cognitive decline. After meticulous data extraction and quality assessment by two independent reviewers, 22 prospective studies and 11 case-control studies involving 389,505 participants were included. According to the investigation, drinking tea or coffee was linked to a lower incidence of cognitive impairments. Subgroup analysis highlighted significant influences of ethnicity, gender, and outcomes on this association. Notably, when it came to coffee and tea drinking, the protective impact seemed greater for males than women. A non-linear correlation between coffee intake and AD risk was observed, with maximum protection at around 2.5 cups/day. Conversely, a linear relationship was identified between tea consumption and cognitive disorders, with risk decreasing by 11% for every additional cup consumed per day. Overall, the meta-analysis suggests that consuming 2.5 cups of coffee per day could minimize AD risk. In contrast, a daily intake of one cup of tea may lead to an 11% reduction in cognitive deficits. These findings imply that incorporating coffee and tea into dietary interventions could potentially mitigate the onset of dementia.
Association of lifestyle and genetic risk with incidence of dementia
CNP Research Summary can be found in the CNP Library Membership
Age-related cognitive decline may be moderated by frequency of specific food products consumption
Small targeted dietary changes can yield substantial gains for human health and the environment
CNP Research Summary can be found in the CNP Library Membership
Long-term dietary flavonoid intake and subjective cognitive decline in US men and women
CNP Research Summary can be found in the CNP Library Membership
Memory improvements in elderly women following 16 weeks treatment with a combined multivitamin, mineral and herbal supplement
CNP Research Summary can be found in the CNP Library Membership
Diet and biomarkers of Alzheimer’s disease: a systematic review and meta-analysis
Dietary pattern, inflammation and cognitive decline: The Whitehall II prospective cohort study
CNP Research Summary can be found in the CNP Library Membership
In pursuit of healthy aging: Effects of nutrition on brain function
Adherence to a Mediterranean diet is associated with cognitive function in an older non-Mediterranean sample: findings from the Maine-Syracuse Longitudinal Study