Supplemental substances derived from foods as adjunctive therapeutic agents for treatment of neurodegenerative diseases and disorders
CNP Research Summary can be found in the CNP Library Membership
The CNP Diet, Aging, and Neurodegeneration Research Category consolidates research exploring the interdependent relationship between dietary intake and aging and neurodegeneration. To view each original study on the open internet, click “Original.” To view the CNP-written abstract summary, click “CNP Summary.” While only some CNP-written abstract summaries are available below for free, all abstract summaries are available to CNP members through the CNP Library Membership.
Various epidemiological studies have explored the link between coffee or tea consumption and the likelihood of cognitive disorders, yet findings have been inconclusive. To further the understanding of this topic, Zhu et al. (2024) conducted a comprehensive review and meta-analysis to examine the impact of coffee, tea, and caffeine intake on cognitive disorder risk. The review searched PubMed, Embase, and Web of Science databases up to January 2022, gathering studies on dementia, Alzheimer's disease (AD), and cognitive decline. After meticulous data extraction and quality assessment by two independent reviewers, 22 prospective studies and 11 case-control studies involving 389,505 participants were included. According to the investigation, drinking tea or coffee was linked to a lower incidence of cognitive impairments. Subgroup analysis highlighted significant influences of ethnicity, gender, and outcomes on this association. Notably, when it came to coffee and tea drinking, the protective impact seemed greater for males than women. A non-linear correlation between coffee intake and AD risk was observed, with maximum protection at around 2.5 cups/day. Conversely, a linear relationship was identified between tea consumption and cognitive disorders, with risk decreasing by 11% for every additional cup consumed per day. Overall, the meta-analysis suggests that consuming 2.5 cups of coffee per day could minimize AD risk. In contrast, a daily intake of one cup of tea may lead to an 11% reduction in cognitive deficits. These findings imply that incorporating coffee and tea into dietary interventions could potentially mitigate the onset of dementia.
Supplemental substances derived from foods as adjunctive therapeutic agents for treatment of neurodegenerative diseases and disorders
CNP Research Summary can be found in the CNP Library Membership
Effects of a mixed berry beverage on cognitive functions and cardiometabolic risk markers; A randomized cross-over study in healthy older adults
Prospective association between adherence to the MIND diet and subjective memory complaints in the French NutriNet-Santé cohort
CNP Research Summary can be found in the CNP Library Membership
MIND diet associated with reduced incidence and delayed progression of Parkinsonism in old age
Mediterranean-dash intervention for neurodegenerative delay (MIND) diet slows cognitive decline after stroke
CNP Research Summary can be found in the CNP Library Membership
A randomised controlled intervention trial evaluating the efficacy of a Mediterranean dietary pattern on cognitive function and psychological wellbeing in healthy older adults: the MedLey study
Nutritional ketosis as an intervention to relieve astrogliosis: Possible therapeutic applications in the treatment of neurodegenerative and neuroprogressive disorders
CNP Research Summary can be found in the CNP Library Membership
A systematic review of behavioural interventions promoting healthy eating among older people
Long-term dietary flavonoid intake and risk of Alzheimer disease and related dementias in the Framingham Offspring Cohort
CNP Research Summary can be found in the CNP Library Membership