Diet and Inflammation (Adult Population)

The CNP Diet and Inflammation Research Category consolidates research exploring the relationship between dietary intake, inflammation and all aspects of psychological and mental health. To view each original study on the open internet, click “Original.” To view the CNP-written abstract summary, click “CNP Summary.” While only some of the CNP-written abstract summaries are available below for free, all abstract summaries are available to CNP members through the CNP Library Membership.

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FEATURED CNP RESEARCH SUMMARY

Food for mood: relevance of nutritional Omega-3 Fatty acids for depression and anxiety

This 2018 review looks at the importance of omega-3 polyunsaturated fatty acids (PUFAs) in the prevention and treatment of neuropsychiatric diseases, with a particular focus on depression and anxiety. Docosahexaenoic acid (DHA) is an example of an omega-3 PUFA that has been receiving attention for its relevance to many brain diseases. Moreover, Larrieu & Layé discuss the mechanisms in which these omega-3 PUFAs can modulate neurobiological processes involved in the pathophysiology of anxiety and depression. It is mentioned that high concentrations of polyunsaturated fatty acids are present in the brain, which may be explained by PUFA’s possibly protective or corrective role in this anatomical region. The authors debate on the involvement of the sensing activity of free fatty acid receptors, and the activity of the PUFA-derived endocannabinoid system and the hypothalamic-pituitary-adrenal axis.

RESEARCH SUMMARIES

Association of high-fat diet with neuroinflammation, anxiety-like defensive behavioral responses, and altered thermoregulatory responses in male rats (animal study)

Diet quality, dietary inflammatory index and body mass index as predictors of response to adjunctive N-acetylcysteine and mitochondrial agents in adults with bipolar disorder: A sub-study of a randomised placebo-controlled trial

Increased Dietary Inflammatory Index is associated with schizophrenia: Results of a case-control study from bahrain

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Association between the dietary inflammatory index and common mental health disorders profile scores

Association between dietary inflammatory index and psychological profile in adults

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Empirically derived food-based dietary inflammatory index is associated with increased risk of psychological disorders in women

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