Diet and Inflammation (Adult Population)

The CNP Diet and Inflammation Research Category consolidates research exploring the relationship between dietary intake, inflammation and all aspects of psychological and mental health. To view each original study on the open internet, click “Original.” To view the CNP-written abstract summary, click “CNP Summary.” While only some of the CNP-written abstract summaries are available below for free, all abstract summaries are available to CNP members through the CNP Library Membership.

CNP Library Membership

FEATURED CNP RESEARCH SUMMARY

Food for mood: relevance of nutritional Omega-3 Fatty acids for depression and anxiety

This 2018 review looks at the importance of omega-3 polyunsaturated fatty acids (PUFAs) in the prevention and treatment of neuropsychiatric diseases, with a particular focus on depression and anxiety. Docosahexaenoic acid (DHA) is an example of an omega-3 PUFA that has been receiving attention for its relevance to many brain diseases. Moreover, Larrieu & Layé discuss the mechanisms in which these omega-3 PUFAs can modulate neurobiological processes involved in the pathophysiology of anxiety and depression. It is mentioned that high concentrations of polyunsaturated fatty acids are present in the brain, which may be explained by PUFA’s possibly protective or corrective role in this anatomical region. The authors debate on the involvement of the sensing activity of free fatty acid receptors, and the activity of the PUFA-derived endocannabinoid system and the hypothalamic-pituitary-adrenal axis.

RESEARCH SUMMARIES

Association of the dietary inflammatory index with depressive symptoms among pre- and post-menopausal women: Findings from the national health and nutrition examination survey (NHANES) 2005–2010

Pro-inflammatory diet and depressive symptoms in the healthcare setting

Association of dietary Inflammatory Index (DII) and depressive disorders

Protective effects of resveratrol on mitochondrial function in the hippocampus improves inflammation-induced depressive-like behavior

Dietary Inflammatory Index and non-communicable disease risk: A narrative review

Inflammation: Opportunities for treatment stratification among individuals diagnosed with mood disorders

Members only

The inflammatory potential of the diet is associated with depressive symptoms in different subgroups of the general population

Mediterranean Diet and low-grade subclinical inflammation: The Moli-sani Study

Members only

Association of high-fat diet with neuroinflammation, anxiety-like defensive behavioral responses, and altered thermoregulatory responses in male rats (animal study)

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