The CNP Diet and Inflammation Research Category consolidates research exploring the relationship between dietary intake, inflammation and all aspects of psychological and mental health. To view each original study on the open internet, click “Original.” To view the CNP-written abstract summary, click “CNP Summary.” While only some of the CNP-written abstract summaries are available below for free, all abstract summaries are available to CNP members through the CNP Library Membership.
This 2018 review looks at the importance of omega-3 polyunsaturated fatty acids (PUFAs) in the prevention and treatment of neuropsychiatric diseases, with a particular focus on depression and anxiety. Docosahexaenoic acid (DHA) is an example of an omega-3 PUFA that has been receiving attention for its relevance to many brain diseases. Moreover, Larrieu & Layé discuss the mechanisms in which these omega-3 PUFAs can modulate neurobiological processes involved in the pathophysiology of anxiety and depression. It is mentioned that high concentrations of polyunsaturated fatty acids are present in the brain, which may be explained by PUFA’s possibly protective or corrective role in this anatomical region. The authors debate on the involvement of the sensing activity of free fatty acid receptors, and the activity of the PUFA-derived endocannabinoid system and the hypothalamic-pituitary-adrenal axis.
CNP Research Summary can be found in the CNP Library Membership
Dietary fiber and its associations with depression and inflammation
Food for mood: Relevance of nutritional omega-3 fatty acids for depression and anxiety
Mitigation of inflammation-induced mood dysregulation by long-chain omega-3 fatty acids
Influence of lifestyle patterns on depression among adults with diabetes: a mediation effect of dietary inflammatory index
CNP Research Summary can be found in the CNP Library Membership
A J-shaped association between Dietary Inflammatory Index (DII) and depression: A cross-sectional study from NHANES 2007-2018
Association of pro-inflammatory diet with frailty onset among adults with and without depressive symptoms: results from the Framingham Offspring Study
CNP Research Summary can be found in the CNP Library Membership
Diet as a hot topic in psychiatry: A population‐scale study of nutritional intake and inflammatory potential in severe mental illness
Association of the dietary inflammatory index with depressive symptoms among pre- and post-menopausal women: Findings from the national health and nutrition examination survey (NHANES) 2005–2010