The effect of a Mediterranean diet on the symptoms of depression in young males (the “AMMEND: A Mediterranean Diet in MEN with Depression” study): a randomized controlled trial

This study examined whether a Mediterranean diet (MD) could improve depressive symptoms in young males (18–25 years) with moderate to severe depression. A 12-week randomized controlled trial compared an MD intervention to befriending therapy, with assessments at baseline, week 6, and week 12. Among 72 participants who completed the study, those in the MD group showed significantly higher Mediterranean Diet Adherence Scores (MEDAS) compared to the control group (mean difference: 7.8; P < 0.001). The MD group also experienced greater reductions in depression severity (BDI-II score mean difference: 14.4; P < 0.001) and improved quality of life (QoL mean difference: 12.7; P < 0.001) at week 12. The findings suggest that an MD can significantly improve depression and quality of life in young males, emphasizing the role of nutrition in mental health treatment. These results may help guide dietary recommendations for this population.

Year: 2022

Reference: Bayes, J., Schloss, J., & Sibbritt, D. (2022). The effect of a Mediterranean diet on the symptoms of depression in young males (the "AMMEND: A Mediterranean Diet in MEN with Depression" study): a randomized controlled trial. The American journal of clinical nutrition, 116(2), 572–580. https://doi.org/10.1093/ajcn/nqac106