Mediterranean diet-based intervention to improve depressive symptoms: analysis of the PREDIDEP randomized trial
The impact of the Mediterranean diet intervention on reducing the risk of depression recurrence or subsyndromal depressive symptoms in patients who have recovered from depression has not been thoroughly studied. To explore the effect of a Mediterranean diet enhanced with extra virgin olive oil on depression recurrence, Cabrera-Suárez et al. (2024) conducted a two-year randomized trial, the PREDIDEP study. The Beck Depression Inventory helped evaluate depressive symptoms at baseline and four, eight, sixteen, twenty, and twenty-four-month follow-ups. After two years, the dietary intervention group (n = 103) showed no significant differences from the control group (n = 93) regarding depression recurrence risk, the primary outcome. However, as secondary outcomes, the intervention group showed improvement in depressive symptoms at four and eight months, whereas the control group showed no changes. Additionally, at 20 months, significant differences between the groups were observed. A Mediterranean diet intervention in patients with a history of depression may help reduce depressive subsyndromal symptoms. [NPID: Mediterranean diet, depression, olive oil, clinical trial]
Year: 2024
