Comparing quality of life in smell and taste disorders with other chronic conditions—a narrative review

Smell and taste disorders (SATDs) affect a growing number of individuals, yet they often go unrecognized, leading to significant detriments in various aspects of life. A recent cohort study provided compelling data through assessments using the Olfactory Disorder Questionnaire (ODQ), EQ-5D-5L (EuroQol Five-Dimension Five-Level), and EQ-5D-5L Visual Analogue Scale (VAS). These findings underscore the profound impact SATDs have on both quality of life and psychological health.

This review aims to illuminate the burden of SATDs by juxtaposing their effects on mental well-being and quality of life against other chronic conditions. Metrics such as the EQ-5D-5L and the Beck Depression Inventory (BDI) facilitate this comparison, drawing on existing literature.

Our literature review encompassed studies published from January 1, 2010, to August 10, 2024, and focused on systematic reviews reporting EQ-5D-5L or BDI scores associated with chronic health issues. The analysis revealed that patients suffering from SATDs exhibit EQ-5D-5L and BDI scores that are on par with individuals experiencing other chronic conditions, including diabetes, stroke, cardiovascular diseases, respiratory issues, and ear, nose, and throat (ENT) disorders.

These results illuminate the substantial burden that olfactory dysfunction imposes on individuals, often comparable to that of better-known chronic illnesses. In contrast to other conditions that have established treatment protocols, effective therapies for SATDs are surprisingly scarce. This points to a significant gap in both research efforts and clinical care. To address this oversight, there is a pressing need for greater awareness and focused research to develop effective treatments. Addressing these issues could play a pivotal role in enhancing outcomes for individuals with SATDs, a population that often remains underestimated in healthcare discussions. [NPID: Taste disorders, chronic conditions, smell, psychology, well-being]

Year: 2026

Reference: Glibbery, N., Turner, D., Boak, D., & Philpott, C. Comparing Quality of Life in Smell and Taste Disorders With Other Chronic Conditions—A Narrative Review. Clinical Otolaryngology. https://doi.org/10.1111/coa.70119

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