Navigation
Effect of nutrition in Alzheimer’s disease: A systematic review
Alzheimer’s disease (AD) is a progressive neurological degenerative condition characterized by diminished cognitive function. There are currently no viable cures for this illness. However, some actions, such as dietary therapies, can halt the development of the condition. This systematic review by Xu Lou et al. (2023) aimed to locate and outline the most recently published updates to the nutritional status of AD patients and nutritional therapies during the last five years. The PubMed, Web of Science, Scopus, and Cochrane Library databases were searched for randomized clinical trials, systematic reviews, and meta-analyses exploring the links between dietary treatments and AD published between 2018 and 2022. A total of 38 papers were found, of which 21 were systematic reviews or meta-analyses, and 17 were randomized clinical trials. Analysis of the results indicated that the Western food pattern increases the likelihood of acquiring AD. In contrast, preventive factors include the Mediterranean diet, the ketogenic diet, and the use of probiotics and omega-3 fatty acid supplements. Only in mild-to-moderate AD instances does this impact become important. The authors conclude that certain dietary modifications may enhance cognitive function and quality of life while slowing the course of AD. To gain a better understanding, additional investigation is needed. [NPID: Alzheimer’s disease, diet, cognitive decline, neurodegenerative disorder, Mediterranean diet, Western Diet, ketogenic diet, systematic review, randomized control trial]
Year: 2023
