Association of composite dietary antioxidant index with depression and all-cause mortality in middle-aged and elderly population

Recent research has increasingly recognized the potential of dietary adjustments as a means to address depression. However, whether the composite dietary antioxidant index (CDAI) is linked to depression and overall mortality in middle-aged and elderly populations remains uncertain. This study by Luo et al. (2024) aimed to investigate these relationships among middle-aged and elderly Americans. Using data from 14997 participants of the NHANES (2007-2018), the authors discovered significant links between CDAI and all-cause mortality and between CDAI and depression after adjusting for all covariates. Notably, a linear association was found between CDAI and depression. At the same time, the relationship between CDAI and all-cause mortality was nonlinear – that is, changes in CDAI did not affect all-cause mortality. The authors conclude that a linear negative relationship was seen between CDAI and depression. In contrast, a nonlinear negative relationship was seen between composite dietary antioxidant index (CDAI) and all-cause mortality in a population of middle-aged and elderly Americans. [NPID: Dietary modifications, depression interventions, middle-aged, elderly, nonlinear relationships]

Year: 2024

Reference: Luo, J., Xu, X., Sun, Y., Lu, X., & Zhao, L. (2024). Association of composite dietary antioxidant index with depression and all-cause mortality in middle-aged and elderly population. Scientific Reports, 14(1), 9809. https://doi.org/10.1038/s41598-024-60322-0

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