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Encyclopedia of Nutritional Psychology

Arcuate Nucleus

Evidence-informed definition Updated June 22, 2025 How to cite this entry

The arcuate nucleus is a cluster of neurons located at the base of the hypothalamus. It plays a central role in regulating appetite, metabolism, and energy balance. This nucleus integrates peripheral signals such as leptin, insulin, and ghrelin, and contains two key neuron populations, one that stimulates feeding (e.g., AgRP/NPY neurons) and one that suppresses it (e.g., POMC neurons), making it a key regulator of homeostatic control over food intake.

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Written by The Center for Nutritional Psychology
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The Center for Nutritional Psychology. (2025). Arcuate Nucleus. In Encyclopedia of Nutritional Psychology. The Center for Nutritional Psychology.

https://www.nutritional-psychology.org/encyclopedia/arcuate-nucleus/
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