Dietary wheat amylase trypsin inhibitors exacerbate CNS inflammation in experimental multiple sclerosis.
The CNP Diet, Chronic Pain and Disability Research Category consolidates research exploring the interdependent relationship between dietary intake, pain, and disability. To view each original study on the open internet, click “Original.” To view the CNP-written abstract summary, click “CNP Summary.” While only some of the CNP-written abstract summaries are available below for free, all abstract summaries are available to CNP members through the CNP Library Membership.
This 2020 systematic review screened 20,316 articles from three large online scientific databases to analyse the current literature on the link between dietary patterns, the components of patients’ diet, and chronic musculoskeletal pain. Twelve eligible studies were included in this review, consisting of nine experimental and three observational studies. Seven out of nine experimental studies reported a pain-relieving effect of dietary changes. Proteins, fat, and sugar intake were all found to be associated with pain intensity and threshold, and also, inadequate consumption of calcium, folate, zinc, magnesium, and vitamin B6 was seen in sufferers of pain from chronic rheumatoid arthritis, whilst patients with fibromyalgia showed a lower intake of carbohydrates, proteins, lipids, vitamin A-E-K, folate, selenium, and zinc. Moreover, chronic pain severity was seen to be positively correlated to fat and sugar intake in osteoarthritis, and pain threshold was positively associated with protein intake in fibromyalgia. Elma et. al (2020) also believe plant-based diets might have pain-relieving effects on chronic musculoskeletal pain.
Dietary wheat amylase trypsin inhibitors exacerbate CNS inflammation in experimental multiple sclerosis.
Association of higher Mediterranean diet adherence with lower prevalence of disability and symptom severity, depression, anxiety, stress, sleep quality, cognitive impairment, and physical inactivity in older adults with multiple sclerosis
CNP Research Summary can be found in the CNP Library Membership
The effect of an anti-inflammatory diet on chronic pain: A pilot study
A low-fat diet improves fatigue in multiple sclerosis: Results from a randomized controlled trial
CNP Research Summary can be found in the CNP Library Membership
Global trends in research of pain–gut-microbiota relationship and how nutrition can modulate this link
Elevated dietary ω-6 polyunsaturated fatty acids induce reversible peripheral nerve dysfunction that exacerbates comorbid pain conditions
CNP Research Summary can be found in the CNP Library Membership
High-fat diet causes mechanical allodynia in the absence of injury or diabetic pathology
Mediterranean diet and changes in frequency, severity, and localization of pain in older adults: The Seniors-ENRICA Cohorts
Relationship between diet and relative risk of pain in a cross-sectional analysis of the REGARDS longitudinal study
CNP Research Summary can be found in the CNP Library Membership