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Microbiota-Gut-Brain Axis and DMHR

Microbiota-Gut-Brain Axis and DMHR (Adult Population)

The CNP Microbiota-Gut-Brain Axis (MGBA) & Mental Health Research Category consolidates research exploring the interconnected relationship between dietary intake, the microbiome, and the gut-brain axis in the adult population. To view each original study on the open internet, click “Original.” To view the CNP-written abstract summary, click “CNP Summary.” While only some of the CNP-written abstract summaries are available below for free, all abstract summaries are available to CNP members through the CNP Library Membership.

Transferring the blues: Depression-associated gut microbiota induces neurobehavioural changes in the rat

  • Karim Maghraby, M.B.B.Ch, M.Sc, Director
  • 17 September 2024
  • Reviewed By CNP STAFF

Coming Soon.

Year: 2016

Reference: Kelly, J. R., Borre, Y., O' Brien, C., Patterson, E., El Aidy, S., Deane, J., Kennedy, P. J., Beers, S., Scott, K., Moloney, G., Hoban, A. E., Scott, L., Fitzgerald, P., Ross, P., Stanton, C., Clarke, G., Cryan, J. F., & Dinan, T. G. (2016). Transferring the blues: Depression-associated gut microbiota induces neurobehavioural changes in the rat. Journal of psychiatric research, 82, 109–118. https://doi.org/10.1016/j.jpsychires.2016.07.019

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Related Studies

Relationship between sleep disorders and gut dysbiosis: What affects what?

  • Karim Maghraby, M.B.B.Ch, M.Sc, Director
  • 17 September 2024
  • Reviewed By CNP STAFF

Recent evidence pointed to the relationship between sleep disorders and the gut microbiome, demonstrating how the microbiome plays a role in overall host health, owing to the role of sleep in psycho-social health maintenance, weight management, and hormone levels. Thus, sleep is subject to derangements due to gut microbiome dysbiosis, just like a myriad of […]

Microbial metabolites tune amygdala neuronal hyperexcitability and anxiety-linked behaviors

  • Karim Maghraby, M.B.B.Ch, M.Sc, Director
  • 17 September 2024
  • Reviewed By CNP Staff

The correlation between gut microbiota composition and anxiety behavior This research investigates the correlation between gut microbiota composition and anxiety behavior, with a particular focus on the neural mechanisms involved. In male C57BL/6J germ-free (GF) mice, an increase in anxiety-related behaviors was observed, which correlated with elevated expression of the immediate early c-Fos gene in […]

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