Seafood consumption, omega-3 fatty acids intake, and life-time prevalence of depression in the PREDIMED-Plus trial

In this work, Sánchez-Villegas et al. (2018) intended to discover the links between seafood consumption, omega-3 polyunsaturated fatty acids (ω-3 PUFA), and the pervasiveness of depression, by analyzing data from the PREDIMED-Plus trial. In a sample of 6,587 participants (where 1,367 of which were found to suffer from depression), dietary intake of seafood and ω-3 PUFA was evaluated using a validated food-frequency questionnaire, while the Beck Depression Inventory-II was used to evaluate symptoms of depression. In their results, the authors discovered no relationship between seafood consumption and depression, while moderate consumption of long-chain ω-3 PUFA (approximately 0.5–1 g/day) was linked to a substantial decrease in the pervasiveness of depression. The authors conclude that moderate dietary intake of fish and long-chain ω-3 PUFAs leads to a decrease in the prevalence of depression. [NPID: Fish, omega-3, eicosapentaenoic acid, docosahexaenoic acid, depression]

Year: 2018

Reference: Sánchez-Villegas, A., Álvarez-Pérez, J., Toledo, E., Salas-Salvadó, J., Ortega-Azorín, C., Zomeño, M., Vioque, J., Martínez, J., Romaguera, D., Pérez-López, J., López-Miranda, J., Estruch, R., Bueno-Cavanillas, A., Arós, F., Tur, J., Tinahones, F., Lecea, O., Martín, V., Ortega-Calvo, M., ... Serra-Majem, L. (2018). Seafood consumption, omega-3 fatty acids intake, and life-time prevalence of depression in the predimed-plus trial. Nutrients, 10(12), 2000. https://doi.org/10.3390/nu10122000