Relationship between the gut microbiome and brain function

The gut microbiome is known to influence host physiological functions, including feeding behaviors. Feeding behaviors are subject to several extrinsic and intrinsic factors such as food palatability, genetic background, and environmental factors. In this study by Ousey et al. (2022), the authors investigated whether feeding behavioral responses to palatable food are controlled by interactions with […]

The hypothalamic-pituitary-adrenal (HPA) axis, which supports responses to outside stimuli, connects the circadian and stress response systems. It is yet unknown, though, how these signals are coordinated. According to this study by Tofani et al. (2024), the HPA axis rhythmicity is regulated by the gut flora. When microbes are depleted, it disrupts the brain’s transcriptome […]