Psychoneuroimmunological approach to gastrointestinal related pain

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Depressive symptoms in inflammatory bowel disease: An extraintestinal manifestation of inflammation

This 2019 review outlines how dysregulation of the gut-brain axis (the bidirectional communication between gut and brain) in irritable bowel disease patients may lead to further inflammation and depression, resulting in a vicious cycle of worsening irritable bowel disease outcomes. Since the intestinal microbiota is closely linked with host immune responses, Moulton et al. explain […]

Low-FODMAP diet is associated with improved quality of life in IBS patients-a prospective observational study

Kortlever et al. (2019) remarks that although the low FODMAP (fermentable oligosaccharide, disaccharide, monosaccharide, and polyol) diet is effective at managing symptoms of irritable bowel syndrome (IBS), the long-term studies have rarely reported quality of life (QoL). This observational study aimed to determine the effect of low-FODMAP diet on long-term QoL, gastrointestinal (GI) and non-GI […]