Mind-altering with the gut: Modulation of the gut-brain axis with probiotics

This 2018 review explored the role of gut microbiota in bidirectional interactions between the gut and the brain, including neural, immune-mediated, and metabolic mechanisms. Recent preclinical and clinical trials revealed that gut microbiota plays an important role in the bidirectional interactions between the gastrointestinal tract, the enteric nervous system, and the central nervous system, which is alarming since alterations in gut microbiota composition may be associated with pathogenesis of various neurological disorders, including stress, autism, depression, Parkinson’s disease, and Alzheimer’s disease. Kim et al. (2018) also highlighted recent advances in the understanding of probiotic modulation of neurological and neuropsychiatric disorders. [NPID: psychiatric illnesses, MGBA, gut-brain axis, gut microbiome, enteric nervous system, neurological disorders, stress, autism, depression, Parkinson’s disease, Alzheimer’s disease]

Year: 2018

Reference: Kim, N., Yun, M., Oh, Y. J., & Choi, H. J. (2018). Mind-altering with the gut: Modulation of the gut-brain axis with probiotics. Journal of microbiology (Seoul, Korea), 56(3), 172–182. https://doi.org/10.1007/s12275-018-8032-4

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