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Marine omega-3 fatty acid supplementation for borderline personality disorder: A meta-analysis
Despite a growing body of research probing the use of omega-3 fatty acids (abundant in fish) in borderline personality disorder (BPD), a lack of clarity remains on their impact on disease outcomes. Through their work, Karaszewska et al. (2021) attempted to appraise the impact of using omega-3 fatty acids in BPD through meta-analyses employing an a priori differentiation (i.e., based on theoretical rather than clinical observation) of affected psychological symptom domains in BPD patients. Through a literature search of several databases (EMBASE, PsycINFO, MEDLINE), and selecting five studies encompassing a 137 BPD patient cohort, the authors discovered a comprehensive impact of omega-3 fatty acids deficiency was found to be linked to increased BPD symptom severity. In particular, omega-3 fatty acid deficiency leads to patients being unable to tolerate negative emotions or events, and may cause them to lose adequate control over impulsive behaviors, compared to controls. The authors conclude that their work highlights the positive impact of marine-derived omega-3 fatty acids on BPD, and determines that they could be evaluated as adjuvant treatments in the course of BPD. [NPID: Omega-3 fatty acids, Borderline Personality Disorder, affective disorder, impulsive behavior, cognition, perception]
Year: 2021
