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Diet and Brain

Diet and Brain (Adult Population)

The CNP Diet and Brain Research Category consolidates research exploring the interdependent relationship between dietary intake and the brain. To view each original study on the open internet, click “Original.” To view the CNP-written abstract summary, click “CNP Summary.” While only some of the CNP-written abstract summaries are available below for free, all abstract summaries are available to CNP members through the CNP Library Membership.

High on food: the interaction between the neural circuits for feeding and for reward

  • Karim Maghraby, M.B.B.Ch, M.Sc, Director
  • 11 October 2020
  • Reviewed By CNP STAFF
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This CNP Research Summary is protected. Become a CNP Library Member to access it.

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Related Studies

Reduced cognitive function, increased blood-brain-barrier transport and inflammatory responses, and altered brain metabolites in LDLr -/-and C57BL/6 mice fed a western diet

  • Karim Maghraby, M.B.B.Ch, M.Sc, Director
  • 11 October 2020
  • Reviewed By CNP STAFF

The purpose of this 2018 study was to determine if a western diet changes brain metabolism, increases blood-brain barrier (BBB) transport and inflammation, and induces cognitive impairment in C57BL/6 (WT) mice and low-density lipoprotein receptor null (LDLr -/-) mice (a model of hyperlipidemia and cognitive decline). Cognitive processes (assessed by Y-maze and radial arm water […]

Distinct basal forebrain-originated neural circuits promote homoeostatic feeding and suppress hedonic feeding in male mice

  • Karim Maghraby, M.B.B.Ch, M.Sc, Director
  • 11 October 2020
  • Reviewed By CNP Staff

Feeding behavior is driven by two main factors: homeostatic needs triggered by hunger and hedonic desires for pleasure, even when not hungry. Although life depends on homeostatic eating, excessive hedonic feeding can result in adverse health effects such as obesity and metabolic diseases. However, the neurobiological mechanisms that regulate homeostatic versus hedonic eating remain poorly […]

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