Crosstalk between the gut microbiota and the brain: An update on neuroimaging findings

Liu et al. (2019) recognised that the mechanisms underlying the association between the alterations in gut microbiota (GM) with neurodevelopmental, neurodegenerative, and psychiatric disorders were mainly based on parallel CNS, endocrine, and immune-related molecular pathways that interact with each other. Due to the scarcity of data on how structural and functional changes in the brain correspond with gut microbiotic states in vivo, this review inspected the recent studies that employed advanced neuroimaging techniques and gut microbiome analyses to study the structure, function, and molecular aspects of brain activity in living healthy human and patient populations. The imaging modalities are discussed before the researchers provide evidence of the human GM profile’s significant association with brain microstructure, intrinsic activities, functional connectivity (FC), cognitive function and mood. [NPID: microbiome, gut-brain axis, gut microbiota, gut bacteria, gastrointestinal tract, digestion, gut permeability, neurodevelopmental disorders, neurodegenerative disorders, psychiatric disorders, cognition, mood]

Year: 2019

Reference: Liu, P., Peng, G., Zhang, N., Wang, B., & Luo, B. (2019). Crosstalk Between the Gut Microbiota and the Brain: An Update on Neuroimaging Findings. Frontiers in neurology, 10, 883. https://doi.org/10.3389/fneur.2019.00883