Boosting the Photoaged Skin: The Potential Role of Dietary Components
Skin photoaging, primarily caused by ultraviolet (UV) radiation, leads to symptoms like dryness, wrinkles, uneven pigmentation, and loss of elasticity. Increasingly, nutraceuticals are being recognized for their potential to prevent and treat these effects. This article reviews current research on the cellular and molecular mechanisms underlying UV-induced skin photoaging and discusses how dietary components can mitigate these effects. Key factors in the photoaging process include matrix metalloproteinases, transforming growth factors, skin fat, inflammation, oxidative stress, damage to DNA, telomere shortening, microRNA, advanced glycation end products, the hypothalamic-pituitary-adrenal axis, and certain ion channels. Evidence from animal studies and clinical trials supports that various dietary components can slow the progression and reduce the symptoms of skin photoaging. These components primarily work by preserving skin moisture, maintaining the extracellular matrix, regulating key signaling pathways, and providing antioxidant benefits. Therefore, consuming food-derived functional components represents a promising approach to combat the damage of skin photoaging. [NPID: Extracellular matrix, fibroblast, nutraceuticals, photoaging, skin]
Year: 2024
