Association of probable post-traumatic stress disorder with dietary pattern and gut microbiome in a cohort of women

Post-traumatic stress disorder (PTSD) can develop in persons who have gone through or seen terrible experiences. It has been proposed that the microbiota-gut-brain axis is crucial for mental health. Ke et al. (2023) evaluated the dietary and gut microbiome data of 191 participants in a substudy of an ongoing longitudinal cohort of women to learn more about PTSD symptoms and traumatic experiences. The authors noted that lower adherence to the Mediterranean diet pattern was related to greater PTSD symptoms. This connection was also linked to certain potentially PTSD-protective species like Eubacterium eligens. In addition, it was shown that PTSD-protective species like Akkermansia muciniphila were primarily responsible for the microbial processes involved in the manufacture of pantothenate and coenzyme A, proven to protect against PTSD. The authors conclude that their results may influence dietary or microbiome-based treatments for PTSD treatment or prevention. [NPID: Metagenomics, microbiome, diet, PTSD, trauma]

Year: 2023

Reference: Ke, S., Wang, XW., Ratanatharathorn, A. et al. Association of probable post-traumatic stress disorder with dietary pattern and gut microbiome in a cohort of women. Nat. Mental Health (2023). https://doi.org/10.1038/s44220-023-00145-6

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