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The germ-free (GF) animal model refers to the study of animals raised in a sterile environment free of microorganisms (i.e., beneficial and pathogenic microbes) for research purposes (Bhattarai & Kashyap, 2016).
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The Center for Nutritional Psychology
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CNP Encyclopedia Editorial Board
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The Center for Nutritional Psychology. (2026). Germ-Free (GF) Animal Model. In Encyclopedia of Nutritional Psychology. The Center for Nutritional Psychology.
https://www.nutritional-psychology.org/encyclopedia/germ-free-gf-animal-model/
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