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Encyclopedia of Nutritional Psychology

Enteric Nervous System (ENS)

Evidence-informed definition Updated March 28, 2026 How to cite this entry

The enteric nervous system (ENS) is a complex network of neurons located in the walls of the gastrointestinal tract, extending from the esophagus to the rectum. Often referred to as the “second brain“, it functions independently and communicates with the central nervous system. In the context of the MGBA, it is an active communication pathway through which the gut influences the brain and vice versa.

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Written by The Center for Nutritional Psychology
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The Center for Nutritional Psychology. (2026). Enteric Nervous System (ENS). In Encyclopedia of Nutritional Psychology. The Center for Nutritional Psychology.

https://www.nutritional-psychology.org/encyclopedia/enteric-nervous-system-ens/
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