Diet and Probiotics

The CNP Diet and Probiotics Research Category consolidates research exploring the interdependent relationship between dietary intake and probiotics. To view each original study on the open internet, click “Original.” To view the CNP summary of the study, click “CNP Summary.” While a small portion of the studies in this research category are available below for free, the full set of studies (and their summaries) are available to CNP members through the CNP Library Membership (available Fall 2021).

2019

Effect of probiotic and prebiotic vs placebo on psychological outcomes in patients with major depressive disorder: A randomized clinical trial

Original

2019

The study evaluating the effect of probiotic supplementation on the mental status, inflammation, and intestinal barrier in major depressive disorder patients using gluten-free or gluten-containing diet (SANGUT study): a 12-week, randomized, double-blind, and placebo-controlled clinical study protocol

Original

2020

The effects of probiotics and prebiotics on mental disorders: A review on depression, anxiety, Alzheimer, and Autism Spectrum Disorders

Original

2016

Clinical and metabolic response to probiotic administration in patients with major depressive disorder: A randomized, double-blind, placebo-controlled trial

Original

2016

Effect of probiotics on depression: A systematic review and meta-analysis of randomized controlled trials

Original

2019

Prebiotics and probiotics for depression and anxiety: A systematic review and meta-analysis of controlled clinical trials

Original

2019

Probiotic food consumption is associated with lower severity and prevalence of depression: A nationwide cross-sectional study

Original

2019

Effect of probiotic interventions on depressive symptoms: A narrative review evaluating systematic reviews

Original

2020

Effects of a psychobiotic supplement on serum brain-derived neurotrophic factor levels in depressive patients: A post hoc analysis of a randomized clinical trial

Original

2018

Effect of a multistrain probiotic (Lactoflorene ® Plus) on inflammatory parameters and microbiota composition in subjects with stress-related symptoms

Original

2019

Gut feeling: randomized controlled trials of probiotics for the treatment of clinical depression: Systematic review and meta-analysis

Original

2018

Probiotics for the treatment of depressive symptoms: An anti-inflammatory mechanism?

Original

2017

Probiotic Bifidobacterium longum NCC3001 Reduces Depression Scores and Alters Brain Activity: A Pilot Study in Patients With Irritable Bowel Syndrome

Original

2020

Supplementation with combined Lactobacillus helveticus R0052 and Bifidobacterium longum R0175 across development reveals sex differences in physiological and behavioural effects of western diet in Long–Evans rats (animal)

Original

2016

Probiotic supplementation can positively affect anxiety and depressive symptoms: a systematic review of randomized controlled trials

Original

2019

The gut-brain relationship: Investigating the effect of multispecies probiotics on anxiety in a randomized placebo-controlled trial of healthy young adults

Original

2018

The effects of probiotics on mood and emotion

Original

2019

Probiotic supplementation attenuates hippocampus injury and spatial learning and memory impairments in a cerebral hypoperfusion mouse model

Original

2019

Microbiota and memory: A symbiotic therapy to counter cognitive decline?

Original

2015

A randomized controlled trial to test the effect of multispecies probiotics on cognitive reactivity to sad mood

Original

2018

A meta-analysis of the use of probiotics to alleviate depressive symptoms

Original

2017

Probiotics and subclinical psychological symptoms in healthy participants: A systematic review and meta-analysis

Original

2020

Probiotics in psychosocial stress and anxiety. A systematic review

Original

2018

The anxiolytic effect of probiotics: A systematic review and meta-analysis of the clinical and preclinical literature

Original

2017

Lost in translation? The potential psychobiotic Lactobacillus rhamnosus (JB-1) fails to modulate stress or cognitive performance in healthy male subjects

Original

2019

Probiotic Lactobacillus Plantarum 299v decreases kynurenine concentration and improves cognitive functions in patients with major depression: A double-blind, randomized, placebo controlled study

Original

2018

Adjunctive probiotic microorganisms to prevent rehospitalization in patients with acute mania: A randomized controlled trial

Original

2019

Probiotics: a potential immunotherapeutic approach for the treatment of schizophrenia

Original

2020

Oral administration of S-Adenosylmethionine (SAMe) and Lactobacillus Plantarum HEAL9 improves the mild-to-moderate symptoms of depression: A randomized, double-blind, placebo-controlled study

Original