Diet and Brain

The CNP Diet and Brain Research Category consolidates research exploring the interdependent relationship between dietary intake and the brain. To view each original study on the open internet, click “Original.” To view the CNP-written abstract summary, click “CNP Summary.” While only some of the CNP-written abstract summaries are available below for free, all abstract summaries are available to CNP members through the CNP Library Membership.

New

2023

Chronic hyperpalatable diet induces impairment of hippocampal-dependent memories and alters glutamatergic and fractalkine axis signaling

Original

2024

Western diet consumption impairs memory function via dysregulated hippocampus acetylcholine signaling

Original
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CNP Research Summary can be found in the CNP Library Membership

2024

Associations of dietary patterns with brain health from behavioral, neuroimaging, biochemical, and genetic analyses

Original

2024

Control of feeding by a bottom-up midbrain-subthalamic pathway

Original

2024

Post-operative cognitive dysfunction is exacerbated by high-fat diet via TLR4 and prevented by dietary DHA supplementation

Original
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CNP Research Summary can be found in the CNP Library Membership

2024

The hedonic overdrive model best explains high-fat diet-induced obesity in C57BL/6 mice

Original

2023

Higher fresh fruit intake relates to larger grey matter volumes in areas involved in dementia and depression: A UK Biobank study.

Original

2018

Sugar beverages and dietary sodas impact on brain health: A mini literature review

Original
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CNP Research Summary can be found in the CNP Library Membership

2023

Internal-state-dependent control of feeding behavior via hippocampal ghrelin signaling

Original

2023

Diet-induced glial insulin resistance impairs the clearance of neuronal debris

Original
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CNP Research Summary can be found in the CNP Library Membership

2023

Hypothalamic volume is associated with body mass index

Original

2023

Dietary magnesium intake is related to larger brain volumes and lower white matter lesions with notable sex differences

Original
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CNP Research Summary can be found in the CNP Library Membership

2023

An intestinal sphingolipid confers intergenerational neuroprotection

Original

2023

Longer-term mixed nut consumption improves brain vascular function and memory: A randomized, controlled crossover trial in older adults

Original

2023

Critical role of lateral habenula circuits in the control of stress-induced palatable food consumption

Original

2023

Effect of nutrition in Alzheimer’s disease: A systematic review

Original
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CNP Research Summary can be found in the CNP Library Membership

2020

Vitamins and minerals for energy, fatigue and cognition: A narrative review of the biochemical and clinical evidence

Original

2020

Diet and mental health: Review of the recent updates on molecular mechanisms

Original

2023

Differential regulation of nucleus accumbens glutamate and GABA in obesity-prone and obesity-resistant rats

Original

2023

Dietary magnesium intake is related to larger brain volumes and lower white matter lesions with notable sex differences

Original
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CNP Research Summary can be found in the CNP Library Membership

2012

Self-reported dietary intake of potassium, calcium, and magnesium and risk of dementia in the Japanese: the Hisayama Study

2023

Habitual daily intake of a sweet and fatty snack modulates reward processing in humans

Original
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CNP Research Summary can be found in the CNP Library Membership

2018

Lateral hypothalamic area neurotensin neurons are required for control of orexin neurons and energy balance

Original

2022

Time to drink: Activating lateral hypothalamic area neurotensin neurons promotes intake of fluid over food in a time-dependent manner

Original
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CNP Research Summary can be found in the CNP Library Membership

2020

Manipulations of central amygdala neurotensin neurons alter the consumption of ethanol and sweet fluids in mice

Original

2022

A circuit from lateral septum neurotensin neurons to tuberal nucleus controls hedonic feeding

Original
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CNP Research Summary can be found in the CNP Library Membership

2023

Differential regulation of nucleus accumbens glutamate and GABA in obesity-prone and obesity-resistant rats

2022

Neurotensin neurons in the extended amygdala control dietary choice and energy homeostasis

Original
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CNP Research Summary can be found in the CNP Library Membership

2022

Chronic consumption of cranberries (Vaccinium macrocarpon) for 12 weeks improves episodic memory and regional brain perfusion in healthy older adults: A randomised, placebo-controlled, parallel-groups feasibility study

Original

2022

Long term high fat diet induces metabolic disorders and aggravates behavioral disorders and cognitive deficits in MAPT P301L transgenic mice

Original
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CNP Research Summary can be found in the CNP Library Membership

2020

Western diet: implications for brain function and behavior

Original

2021

Obesity and sex-related associations with differential effects of sucralose vs sucrose on appetite and reward processing: A randomized crossover trial

Original
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CNP Research Summary can be found in the CNP Library Membership

2020

Reframing appetitive reinforcement learning and reward valuation as effects mediated by hippocampal-dependent behavioral inhibition

Original

2021

In pursuit of healthy aging: Effects of nutrition on brain function

Original
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CNP Research Summary can be found in the CNP Library Membership

2020

Dietary diversity Is associated with memory status in chinese adults: A prospective study

Original

2021

Green tea consumption is associated with annual changes in hippocampal volumes: A longitudinal study in community-dwelling middle-aged and older Japanese individuals

Original
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CNP Research Summary can be found in the CNP Library Membership

2021

Dietary diversity is associated with longitudinal changes in hippocampal volume among Japanese community dwellers

Original

2017

Nutritional factors affecting adult neurogenesis and cognitive function

Original
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CNP Research Summary can be found in the CNP Library Membership

2021

High fructose corn syrup-moderate fat diet potentiates anxio-depressive behavior and alters ventral striatal neuronal signaling

Original
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CNP Research Summary can be found in the CNP Library Membership

2019

High-fat diet worsens the impact of aging on microglial function and morphology in a region-specific manner (animal)

Original

2020

Withdrawal from extended, intermittent access to a highly palatable diet impairs hippocampal memory function and neurogenesis: effects of memantine

Original
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CNP Research Summary can be found in the CNP Library Membership

2011

Higher reported saturated fat and refined sugar intake is associated with reduced hippocampal-dependent memory and sensitivity to interoceptive signals

Original

2018

Reduced cognitive function, increased blood-brain-barrier transport and inflammatory responses, and altered brain metabolites in LDLr -/-and C57BL/6 mice fed a western diet

Original
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CNP Research Summary can be found in the CNP Library Membership

2020

Impaired brain homeostasis and neurogenesis in diet-induced overweight zebrafish: a preventive role from A. borbonica extract (animal)

Original

2020

Mitochondrial dynamics in the brain are associated with feeding, glucose homeostasis, and whole-body metabolism

Original
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CNP Research Summary can be found in the CNP Library Membership

2015

High on food: the interaction between the neural circuits for feeding and for reward

Original

2018

Hedonic eating and the "delicious circle": From lipid-derived mediators to brain dopamine and back