Diet and Brain

The CNP Diet and Brain Research Category consolidates research exploring the interdependent relationship between dietary intake and the brain. To view each original study on the open internet, click “Original.” To view the CNP summary of the study, click “CNP Summary.” While a small portion of the studies in this research category is available below for free, the full set of studies (and their summaries) are available to CNP members through the CNP Library Membership (available Fall 2021).

2020

Hippocampal-dependent appetitive control is impaired by experimental exposure to a Western-style diet

Original

2017

High-fat diet and aging interact to produce neuroinflammation and impair hippocampal- and amygdalar-dependent memory

Original

2019

Dietary fructose-induced gut dysbiosis promotes mouse hippocampal neuroinflammation: a benefit of short-chain fatty acids

Original

2011

Western diet consumption and cognitive impairment: links to hippocampal dysfunction and obesity

Original

2018

Chronic consumption of a western diet modifies the DNA methylation profile in the frontal cortex of mice (animal)

Original

2016

A high-fat diet decreases GABA concentration in the frontal cortex and hippocampus of rats (animal)

Original

2019

A high-fat high-sugar diet in adolescent rats impairs social memory and alters chemical markers characteristic of atypical neuroplasticity and parvalbumin interneuron depletion in the medial prefrontal cortex (animal)

Original

2018

Long term Westernized diet leads to region-specific changes in brain signaling mechanisms (animal)

Original

2017

High-fat diet and aging interact to produce neuroinflammation and impair hippocampal- and amygdalar-dependent memory (animal)

Original

2016

High-fat diet Induced anxiety and anhedonia: Impact on brain homeostasis and inflammation (animal)

Original

2002

A high-fat, refined sugar diet reduces hippocampal brain-derived neurotrophic factor, neuronal plasticity, and learning

Original

2019

A high-fat diet promotes depression-like behavior in mice by suppressing hypothalamic PKA signaling (animal study)

Original

2018

Association of long-term diet quality with hippocampal volume: longitudinal cohort study

Original

2019

Dietary fructose-induced gut dysbiosis promotes mouse hippocampal neuroinflammation: a benefit of short-chain fatty acids

Original

2020

Dietary sugar inhibits satiation by decreasing the central processing of sweet taste

Original

2020

Ghrelin and orexin interact to increase meal size through a descending hippocampus to hindbrain signaling pathway

Original

2018

Hedonic eating and the "delicious circle": From lipid-derived mediators to brain dopamine and back

Original

2015

High on food: the interaction between the neural circuits for feeding and for reward

Original

2020

Mitochondrial dynamics in the brain are associated with feeding, glucose homeostasis, and whole-body metabolism

Original

2020

Impaired brain homeostasis and neurogenesis in diet-induced overweight zebrafish: a preventive role from A. borbonica extract (animal)

Original

2018

Reduced cognitive function, increased blood-brain-barrier transport and inflammatory responses, and altered brain metabolites in LDLr -/-and C57BL/6 mice fed a western diet

Original

2011

Higher reported saturated fat and refined sugar intake is associated with reduced hippocampal-dependent memory and sensitivity to interoceptive signals

Original

2020

Withdrawal from extended, intermittent access to a highly palatable diet impairs Hippocampal memory function and neurogenesis: effects of Memantine

Original

2019

High-fat diet worsens the impact of aging on microglial function and morphology in a region-specific manner (animal)

Original

2013

Adaptations in brain reward circuitry underlie palatable food cravings and anxiety induced by high-fat diet withdrawal

Original

2021

High Fructose Corn Syrup-Moderate Fat Diet Potentiates Anxio-Depressive Behavior and Alters Ventral Striatal Neuronal Signaling

Original

2017

Nutritional factors affecting adult neurogenesis and cognitive function

Original

2021

Dietary diversity is associated with longitudinal changes in hippocampal volume among Japanese community dwellers

Original

2021

Green tea consumption is associated with annual changes in hippocampal volumes: A longitudinal study in community-dwelling middle-aged and older Japanese individuals

Original

2020

Dietary diversity Is associated with memory status in chinese adults: A prospective study

Original

2021

In pursuit of healthy aging: Effects of nutrition on brain function

Original

2020

Reframing appetitive reinforcement learning and reward valuation as effects mediated by hippocampal-dependent behavioral inhibition

Original