The CNP Diet, Aging, and Neurodegeneration Research Category consolidates research exploring the interdependent relationship between dietary intake and aging and neurodegeneration. To view each original study on the open internet, click “Original.” To view the CNP-written abstract summary, click “CNP Summary.” While only some CNP-written abstract summaries are available below for free, all abstract summaries are available to CNP members through the CNP Library Membership.
Various epidemiological studies have explored the link between coffee or tea consumption and the likelihood of cognitive disorders, yet findings have been inconclusive. To further the understanding of this topic, Zhu et al. (2024) conducted a comprehensive review and meta-analysis to examine the impact of coffee, tea, and caffeine intake on cognitive disorder risk. The review searched PubMed, Embase, and Web of Science databases up to January 2022, gathering studies on dementia, Alzheimer's disease (AD), and cognitive decline. After meticulous data extraction and quality assessment by two independent reviewers, 22 prospective studies and 11 case-control studies involving 389,505 participants were included. According to the investigation, drinking tea or coffee was linked to a lower incidence of cognitive impairments. Subgroup analysis highlighted significant influences of ethnicity, gender, and outcomes on this association. Notably, when it came to coffee and tea drinking, the protective impact seemed greater for males than women. A non-linear correlation between coffee intake and AD risk was observed, with maximum protection at around 2.5 cups/day. Conversely, a linear relationship was identified between tea consumption and cognitive disorders, with risk decreasing by 11% for every additional cup consumed per day. Overall, the meta-analysis suggests that consuming 2.5 cups of coffee per day could minimize AD risk. In contrast, a daily intake of one cup of tea may lead to an 11% reduction in cognitive deficits. These findings imply that incorporating coffee and tea into dietary interventions could potentially mitigate the onset of dementia.
The role of diet as a modulator of the inflammatory process in neurological diseases
Dietary patterns and Alzheimer's Disease: An updated review linking nutrition to neuroscience
Adjustment of the MIND diet tool for discriminating Greek patients with dementia: A confirmatory factor analysis
CNP Research Summary can be found in the CNP Library Membership
Mediterranean Diet, Ketogenic Diet or MIND Diet for aging populations with cognitive decline: A systematic review
Investigating nutrient biomarkers of healthy brain aging: a multimodal brain imaging study
Evaluation of dietary intake in individuals with Mild Cognitive Impairment
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Moderate coffee or tea consumption decreased the risk of cognitive disorders: an updated dose–response meta-analysis
Blood-brain barrier disruption: mechanistic links between Western diet consumption and dementia
Consumption of olive oil and diet quality and risk of dementia-related death
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High-fat diets in animal models of Alzheimer’s disease: How can eating too much fat increase Alzheimer’s disease risk?
The impact of continuous and intermittent ketogenic diets on cognitive behavior, motor function, and blood lipids in TgF344-AD rats
Diet, pace of biological aging, and risk of Dementia in the Framingham Heart Study
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An investigation into the potential association between nutrition and Alzheimer's disease
Ketone bodies mediate alterations in brain energy metabolism and biomarkers of Alzheimer’s disease
Therapeutic effects of catechins in less common neurological and neurodegenerative disorders
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Green tea catechins attenuate neurodegenerative diseases and cognitive deficits
Use of curcumin, a natural polyphenol for targeting molecular pathways in treating age-related neurodegenerative diseases
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Diet and lifestyle impact the development and progression of Alzheimer’s dementia
US older adults that consume avocado or guacamole have better cognition than non-consumers: National health and nutrition examination survey 2011–2014
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High consumption of whole grain foods decreases the risk of dementia and Alzheimer's disease: Framingham Offspring Cohort
Beneficial effects of nut consumption on cognitive function among elderly: Findings from a 6-year cohort study
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The relationship of omega-3 fatty acids with dementia and cognitive decline: Evidence from prospective cohort studies of supplementation, dietary intake, and blood markers
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Blueberry supplementation in midlife for dementia risk reduction
Association between dietary patterns and depression in Chinese older adults: A longitudinal study based on CLHLS
Eggs consumption in relation to lower risk of cognitive impairment in elderly: Findings from a 6-year cohort study
Can the Mediterranean diet decrease the risk of depression in older persons - a systematic review
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Association between dietary patterns and depression in Chinese older adults: A longitudinal study based on CLHLS
Eggs consumption in relation to lower risk of cognitive Impairment in elderly: Findings from a 6-Year cohort study
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Trends in diet quality among older US adults from 2001 to 2018
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Effects of berry anthocyanins on cognitive performance, vascular function and cardiometabolic risk markers: A systematic review of randomized placebo-controlled intervention studies in humans
Longer-term soy nut consumption improves cerebral blood flow and psychomotor speed: results of a randomized, controlled crossover trial in older men and women
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Association of lifestyle and genetic risk with incidence of dementia
Age-related cognitive decline may be moderated by frequency of specific food products consumption
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Small targeted dietary changes can yield substantial gains for human health and the environment
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Long-term dietary flavonoid intake and subjective cognitive decline in US men and women
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Memory improvements in elderly women following 16 weeks treatment with a combined multivitamin, mineral and herbal supplement
Diet and biomarkers of Alzheimer's disease: a systematic review and meta-analysis
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Dietary pattern, inflammation and cognitive decline: The Whitehall II prospective cohort study
Adherence to a Mediterranean diet is associated with cognitive function in an older non-Mediterranean sample: findings from the Maine-Syracuse Longitudinal Study
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Supplemental substances derived from foods as adjunctive therapeutic agents for treatment of neurodegenerative diseases and disorders
Effects of a mixed berry beverage on cognitive functions and cardiometabolic risk markers; A randomized cross-over study in healthy older adults
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Prospective association between adherence to the MIND diet and subjective memory complaints in the French NutriNet-Santé cohort
MIND diet associated with reduced incidence and delayed progression of Parkinsonism in old age
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Mediterranean-dash intervention for neurodegenerative delay (MIND) diet slows cognitive decline after stroke
A randomised controlled intervention trial evaluating the efficacy of a Mediterranean dietary pattern on cognitive function and psychological wellbeing in healthy older adults: the MedLey study
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Nutritional ketosis as an intervention to relieve astrogliosis: Possible therapeutic applications in the treatment of neurodegenerative and neuroprogressive disorders
A systematic review of behavioural interventions promoting healthy eating among older people
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Long-term dietary flavonoid intake and risk of Alzheimer disease and related dementias in the Framingham Offspring Cohort
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Findings of a pilot study investigating the effects of Mediterranean diet and aerobic exercise on cognition in cognitively healthy older people living independently within aged-care facilities: the Lifestyle Intervention in Independent Living Aged Care (LIILAC) study
Dietary inflammatory index and the risk of frailty among older adults: a systematic review and meta-analysis
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Lifestyle modifications and nutritional interventions in aging-associated cognitive decline and Alzheimer’s Disease
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HbA1c, diabetes and cognitive decline: the English Longitudinal Study of Ageing
Mediterranean diet, food consumption and risk of late-life depression: The Mugello Study
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Dietary patterns and cognitive health in older adults: A systematic review
Potential for diet to prevent and remediate cognitive deficits in neurological disorders
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Insulin resistance and oxidative stress in the brain: what’s new?
Lifestyle modulators of neuroplasticity: how physical activity, mental engagement, and diet promote cognitive health during aging
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Association between diet quality and frailty prevalence in the Physicians' Health Study
CoQ10 and cognition a review and study protocol for a 90-Day randomized controlled trial investigating the cognitive effects of ubiquinol in the healthy elderly
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Study protocol: associations between dietary patterns, cognitive function and metabolic syndrome in older adults - a cross-sectional study
A novel anti-inflammatory role of Omega-3 PUFAs in prevention and treatment of atherosclerosis and vascular cognitive impairment and dementia
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Dietary protein and amino acid intake: links to the maintenance of cognitive health
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Association between diets and mild cognitive impairment in adults aged 50 years or older
Increased consumption of fruit and vegetables is related to a reduced risk of cognitive impairment and dementia: meta-analysis
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MIND not Mediterranean diet related to 12-year incidence of cognitive impairment in an Australian longitudinal cohort study
The Mediterranean, dietary approaches to stop hypertension (DASH), and Mediterranean-DASH intervention for neurodegenerative delay (MIND) diets are associated with less cognitive decline and a lower risk of Alzheimer's disease-a review
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Mediterranean and MIND diets containing olive biophenols reduces the prevalence of Alzheimer's disease
Gut health, nutrient intake and well-being in community-dwelling older adults
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Association of diet quality and vegetable variety with the risk of cognitive decline in Chinese older adults
The role of nutrition in cognitive function and brain ageing in the elderly
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Adherence to Mediterranean diet and risk of developing cognitive disorders: An updated systematic review and meta-analysis of prospective cohort studies
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Diet and inflammation in cognitive ageing and Alzheimer’s Disease
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Plant-based dietary patterns, plant foods, and age-related cognitive decline
Diet and Alzheimer's dementia - nutritional approach to modulate inflammation
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Depression in middle and older adulthood: the role of immigration, nutrition, and other determinants of health in the Canadian longitudinal study on aging
Mediterranean diet nutrients to turn the tide against insulin resistance and related diseases
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Mediterranean diet and cognitive health: initial results from the Hellenic Longitudinal Investigation of Ageing and Diet
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The role of nutrients in reducing the risk for noncommunicable diseases during aging
The impact of nutrition and intestinal microbiome on elderly depression-a systematic review
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Influence of the mediterranean and ketogenic diets on cognitive status and decline: a narrative review
The role of diet in preventing and reducing cognitive decline