Micronutrients and Mental Health (Adult Population)

The CNP Micronutrients and Mental Health Research Category consolidates research exploring the interdependent relationship between dietary intake and micronutrients. To view each original study on the open internet, click “Original.” To view the CNP-written abstract summary, click “CNP Summary.” While only some of the CNP-written abstract summaries are available below for free, all abstract summaries are available to CNP members through the CNP Library Membership.

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FEATURED CNP RESEARCH SUMMARY

Dietary creatine intake and depression risk among U.S. adults

Bakian et al. (2020) examined the association between dietary creatine and depression in U.S. adults, using the data on dietary creatine intakes and patient health questionnaires obtained by the 2005 to 2012 National Health and Nutrition Examination Survey (NHANES) on its 22,692 participants (aged ≥20 years). This study compared the depression prevalence in the subjects in the lowest quartile of dietary creatine intake (rate of 10.23/100) to the occurrence in those in the highest quartile of creatine consumption (5.98/100 persons). While an inverse association was confirmed between dietary creatine and depression [adjusted odds ratio (AOR) = 0.68], the strongest correlations were seen in females (AOR = 0.62) and participants not taking antidepressant/anxiolytic medication (AOR = 0.58). These results highlighted a significant negative relationship between creatine intake and depression in a nationally representative cohort. This leaves the role that creatine plays in depression among women and across the lifespan to be investigated in the future.

RESEARCH SUMMARIES

Zinc supplementation combined with antidepressant drugs for treatment of patients with depression: A systematic review and meta-analysis

Vitamin C supplementation promotes mental vitality in healthy young adults: Results from a cross-sectional analysis and a randomized, double-blind, placebo-controlled trial

CNP Research Summary can be found in the CNP Library Membership

Effect of vitamin D supplementation on outcomes in people with early psychosis: The DFEND randomized clinical trial

Superiority of magnesium and vitamin B6 over magnesium alone on severe stress in healthy adults with low magnesemia: A randomized, single-blind clinical trial

CNP Research Summary can be found in the CNP Library Membership

Role of magnesium supplementation in the treatment of depression: A randomized clinical trial

Risk factors for depression. New evidence on selenium deficiency and depressive

CNP Research Summary can be found in the CNP Library Membership

An observational preliminary study on the safety of long-term consumption of micronutrients for the treatment of psychiatric symptoms

A randomised trial of nutrient supplements to minimise psychological stress after a natural disaster

CNP Research Summary can be found in the CNP Library Membership

Assessment of dietary adequacy for important brain micronutrients in patients presenting to a traumatic brain injury clinic for evaluation

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