The role of reward circuitry and food addiction in the obesity epidemic: an update
The CNP Diet, Craving, and Food Addiction Research Category explores the psychological, neurobiological, and behavioral interrelations underlying cravings, compulsive overeating, and consumption of highly palatable or ultra-processed foods, highlighting a bidirectional relationship between eating behaviors and dietary intake patterns. Join the CNP Library Membership to learn more.
This 2018 review presents the multifactorial social, neurobehavioral, and metabolic determinants of food intake that influence obesity risk to promote food craving and excessive food intake. The determinants included rewarding foods that stimulate brain reward motivation and stress circuits to influence eating behaviors, as well as stress hormones that hijack the brain’s emotional (limbic) and motivational (striatal) pathways. Sinha (2018) discusses the impact of high-stress levels and trauma, in addition to metabolic alterations such as higher weight, and altered insulin sensitivity, on self-control processes that regulate emotional, motivational, and visceral homeostatic mechanisms of food intake and obesity risk. Also reviewed was the potentially positive interaction between dynamic effects of neurobehavioral adaptations in metabolic, motivation, and stress neurobiology with food craving, excessive food intake, and weight gain. The author highlights key areas that require future investigation to adequately comprehend and address this growing obesity epidemic.
The role of reward circuitry and food addiction in the obesity epidemic: an update
Role of addiction and stress neurobiology on food intake and obesity
CNP Research Summary can be found in the CNP Library Membership
Rethinking food reward
History of early life adversity is associated with increased food addiction and sex-specific alterations in reward network connectivity in obesity
CNP Research Summary can be found in the CNP Library Membership
Fat addiction: psychological and physiological trajectory
Which foods may be addictive? The roles of processing, fat content, and glycemic load
CNP Research Summary can be found in the CNP Library Membership
Food addiction and associations with mental health symptoms: a systematic review with meta-analysis