The study evaluating the effect of probiotic supplementation on the mental status, inflammation, and intestinal barrier in major depressive disorder patients using gluten-free or gluten-containing diet (SANGUT study): A 12-week, randomized, double-blind, and placebo-controlled clinical study protocol

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With the aim of uncovering the effect of microbiota in the gut, through probiotics intervention, on mental health like anxiety and its related factors, this 2019 double-blind, randomization-control study randomly assigned 86 healthy college students (average age 20.6, 75.6% female) to one of five conditions, including 4 probiotic treatments and one placebo, and provided these […]