The role of the gut-brain axis in alcohol use disorders

When people are compelled to consume very appetizing food for enjoyment rather than to meet a caloric demand, this is known as hedonic hunger (HH). HH is not currently recognized as a disorder by the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5). Earlier studies have found correlations in physiology, neurobiology, and therapy […]

Hakimian et al. (2019) developed a new model of chronic opioid exposure that allows self-administration of opioids followed by periods of extinction, to mimic addiction in humans. Using this model, this study demonstrated that a diet high in omega-3 polyunsaturated fatty acids (n-3 PUFAs) can ameliorate oxycodone-seeking behaviors in the absence of drug availability and […]