The HPA axis dysregulation in severe mental illness: Can we shift the blame to gut microbiota?

Niccolai et al. (2019) writes about the multifactorial disorder that is obesity, in which various elements (including genetic, host, and environment) play a definite role, although the etiology has not been fully understood yet. It is hypothesized that the brain could be the seat of the initial malfunction leading to obesity, since neurological comorbidities such […]

Gut microbiota and mental health are closely connected through the gut-brain axis—a complex, bidirectional communication network between the gut and the central nervous system (CNS). The billions of bacteria that make up the human gut microbiome influence immune function, brain development, and digestion. Disruptions in this system have been linked to mood disorders such as […]