The HPA axis dysregulation in severe mental illness: Can we shift the blame to gut microbiota?

In order to examine the causative association between gut microbiota and the onset of irritable bowel syndrome (IBS), as well as the possible moderating role of depression in this relationship, this study by Huang et al. (2024) used a two-sample Mendelian randomization (MR) technique. Multiple two-sample MR methods were utilized to examine the causal effects […]

This 2021 review summarizes the current literature on the relationship between diet, microbiota, and host behavior/brain processes. While diet plays a major role in shaping the gut microbiota composition across the lifespan, people are just beginning to explore whether and how diet can affect the brain via its interactions with the microbiota. Animal studies have […]