Risk factors for depression. New evidence on selenium deficiency and depressive

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The efficacy and safety of nutrient supplements in the treatment of mental disorders: A meta-review of meta-analyses of randomized controlled trials

This 2019 meta-review appraised all the meta-analyses conducted on randomized controlled trials (RCTs) investigating the efficacy and safety of nutrient supplements in common and severe mental disorders. The 33 meta-analyses identified by a systematic search produced outcome data of 10,951 participants. While early evidence suggests polyunsaturated fatty acids (PUFAs) may have positive impacts on attention-deficit/hyperactivity […]

Palmitoylethanolamide counteracts brain fog improving depressive-like behaviour in obese mice: Possible role of synaptic plasticity and neurogenesis

Palmitoylethanolamide (PEA), known for its metabolic and neuroprotective effects, was investigated here by Lama et al. (2020) on its impact on the monoamine system and synaptic plasticity. In this preclinical study C57Bl/6J male mice were fed high-fat diet (HFD) for 12 weeks, before continuing in this trial being fed either 30 mg·kg-1 daily of ultra-micronized […]