Relevance of the anti-inflammatory properties of Curcumin in neurodegenerative diseases and depression

This 2014 review presented the case for curcumin’s potential use as a neuroprotectant and an antidepressant, describing some of its varied mechanisms of action: its possible anti-inflammatory effects and interactions with signal transduction proteins. Tizabi et al. (2014) write that curcumin is believed to be devoid of any side effects and could combat commonly observed co-morbid conditions of neurodegenerative and neuropsychiatric disorders. This review also provides evidence suggesting how this herb’s anti-inflammatory properties have therapeutic potential in treating devastating neurological disorders such as Parkinson’s disease (PD) and neuropsychiatric disorders such as major depressive disorder (MDD). The authors conclude that curcumin or one of its analogs could be of important therapeutic potential in PD and major depression. [NPID: herbs, curcumin, depression, anti-inflammatory, neurological disorders, Parkinson’s disease, Parkinson’s, major depressive disorder, MDD]

Year: 2014

Reference: Tizabi, Y., Hurley, L. L., Qualls, Z., & Akinfiresoye, L. (2014). Relevance of the anti-inflammatory properties of curcumin in neurodegenerative diseases and depression. Molecules (Basel, Switzerland), 19(12), 20864–20879. https://doi.org/10.3390/molecules191220864