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Potential benefits of kefir and its compounds on Alzheimer’s disease: A systematic review
Alzheimer’s disease, marked by a gradual decline in cognitive functions, remains without a definitive cure. Existing therapies focus largely on easing symptoms, particularly behavioral ones, and offer limited impact on the disease’s progression. Emerging research has started to explore kefir’s effects as a potential aid in Alzheimer’s management. Kefir, a fermented drink rich in beneficial microorganisms, may help by positively influencing the gut microbiota, lowering inflammation, and reducing the build-up of harmful brain proteins. Furthermore, kefir contains important bioactive nutrients, such as B vitamins, choline, and folic acid, which support brain health and cognitive performance.
Kefir’s effects on Alzheimer’s disease:
This systematic review by Tanure et al. (2025), conducted in January 2024, investigated kefir’s effects on Alzheimer’s through studies involving animal models and human patients with neurodegenerative conditions, sourced from databases like BVS, Embase, PubMed/MEDLINE, Scopus, and Web of Science. Seven studies were reviewed, featuring invertebrates, rodents, and humans.
Key findings on Animal Studies and Human Trials
In animals, kefir provided antioxidant benefits, lowered beta-amyloid plaque buildup, and reduced vascular and neuronal damage.
Human trials showed reduced inflammatory markers and oxidative stress, alongside memory improvements. These findings suggest kefir may be a useful complementary option in Alzheimer’s care, though additional clinical research is needed.[NPID: Kefir, fermented milk, neurodegenerative diseases, Alzheimer]
Year: 2025
