Nutritional modulation of immune and central nervous system homeostasis: the role of diet in development of neuroinflammation and neurological disease

This 2019 review provides a summary of the current data on the influencing power of nutrition in the immune system and on the development of neuroinflammation and neurological disease. Evidence has been accumulating indicating that dietary patterns can modulate the development of metabolic alterations and inflammation through a variety of methods but many involve the nutrients obtained from the diet affecting microbiome composition, release of microbial products, gastrointestinal signaling molecules, and neurotransmitters. It is these signal molecules that can either promote or inhibit the production of pro-inflammatory cytokines and also the growth of certain leukocyte subpopulations, such as Th17 and Treg cells, which are relevant in the development of neuroinflammatory and neurodegenerative conditions. Estrada & Contreras (2019) support the implementation and maintenance of adequate dietary habits as a strategy to prevent neurological pathologies. [NPID: microbiome, MGBA, gut-brain axis, gut microbiome, inflammation, neurotransmitters, pro-inflammatory cytokines, neurodegenerative conditions]

Year: 2019

Reference: Estrada, J. A., & Contreras, I. (2019). Nutritional Modulation of Immune and Central Nervous System Homeostasis: The Role of Diet in Development of Neuroinflammation and Neurological Disease. Nutrients, 11(5), 1076. https://doi.org/10.3390/nu11051076

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