Neuronutritional approach to Fibromyalgia management: A narrative review

With no obvious underlying structural or pathological causes, fibromyalgia (FM) is a common and complicated disorder marked by widespread chronic pain, exhaustion, sleep problems, and a variety of functional symptoms. Affecting about 1–5% of the global population, particularly women, FM significantly reduces patients’ quality of life, leading to high healthcare costs and decreased productivity. Although FM is common, its precise etiology is still unknown; it is thought to be influenced by genetic, environmental, and psychological variables, including nutrition. There aren’t any widely recognized therapy guidelines at the moment. Thus, symptom alleviation is the primary goal of care. Badaeva et al. (2024) aimed to investigate the possibility of using a neuronutritional approach for fibromyalgia (FM) management in this narrative review. The authors examined the literature on the relationship between nutrition and FM and suggested that dietary changes may be a viable adjunctive therapy. Several nutritional interventions, including supplementation with vitamin D, magnesium, iron, and probiotics, have shown potential in alleviating FM symptoms like chronic pain, anxiety, depression, cognitive issues, sleep disturbances, and gastrointestinal problems. In individuals with FM, weight loss has also been associated with decreased inflammation and an enhanced quality of life. Low-FODMAP and plant-based diets have also been found to have anti-inflammatory properties and offer the potential to treat FM symptoms and related gastrointestinal problems. The review also looks at probiotics, omega-3 fatty acids, melatonin, vitamin D, magnesium, B12, coenzyme Q10, acetyl-l-carnitine, and S-adenosylmethionine. By modifying neurotransmitters, enhancing mitochondrial function, and having anti-inflammatory properties, these substances may help control FM. This analysis highlights the need to treat FM holistically by considering neuronutrition. More investigation and clinical studies are required to create thorough dietary recommendations and improve management techniques for FM patients. [NPID: Chronic pain, dietary interventions, Fibromyalgia, inflammation, neuronutrition, nutritional supplements, quality of life]

Year: 2024

Reference: Badaeva, A., Danilov, A., Kosareva, A., Lepshina, M., Novikov, V., Vorobyeva, Y., & Danilov, A. (2024). Neuronutritional Approach to Fibromyalgia Management: A Narrative Review. Pain and Therapy, 13(5), 1047–1061. https://doi.org/10.1007/s40122-024-00641-2