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MIND diet associated with reduced incidence and delayed progression of Parkinsonism in old age
Agarwal et al. (2018) tested whether there was a correlation between the Mediterranean-DASH Diet Intervention for Neurodegenerative Delay (MIND) diet with incidence and progression of parkinsonism among older adults, by assessing individuals annually for the presence of four parkinsonian signs using a 26-item modified version of the United Parkinson’s Disease Rating Scale. This study involved 706 Memory and Aging Project participants aged 59 −97 years and without parkinsonism at baseline, and defined incident parkinsonism as the first appearance of 2 or more parkinsonism signs over 4.6 years of follow-up while a change in global parkinsonian score signified the progression. Moreover, Mediterranean, and DASH diet pattern scores were computed based on a validated food frequency questionnaire including 144 food items. In adjusted models, greater MIND diet scores correlated to less incidence of parkinsonism (hazard risk = 0.89) as well as slower progression of the disorder [(β= −0.008; SE=0.0037; p=0.04)]. Also, the Mediterranean diet was marginally associated with reduced parkinsonism progression, while the DASH diet was not associated with either outcome. This study found the MIND diet to be associated with a decreased risk and slower progression of parkinsonism among older adults. [NPIDs: aging, elderly, cognitive decline, neurodegenerative disorders, dementia, cognition, Mediterranean diet, DASH, Parkinson’s]
Year: 2018
