Meta-analysis of alcohol induced gut dysbiosis and the resulting behavioral impact

According to Qamar et al. (2019), the gut microbiome plays an important role in the body and contributes to digestive health, the immune system, and brain function. Changes in the diversity of the microbiota is said to influence human physiology and has been implicated in inflammation, depression, obesity, and addiction. Some animal studies have suggested that the gut microbiome even plays a role in the regulation of pain, emotion, and cognition. Furthermore, alcoholism has been associated with gut microbiome dysbiosis (disruption of gut microbiota balance) and can therefore have detrimental effects on the gut-brain axis balance. Imbalances in the microbiome have also been correlated with behavioral changes and alcohol dependence in the host. The aim of this study was to prove the connection between alcohol-induced gut microbiota dysbiosis and any behavioral consequences, through identification and analysis of relevant research. [NPID: substance use, addiction, drugs, inflammation, digestive health, the immune system, brain function, microbiota, inflammation, depression, obesity, addiction, pain, emotional regulation, cognition, dysbiosis, gut-brain axis]

Year: 2019

Reference: Qamar, N., Castano, D., Patt, C., Chu, T., Cottrell, J., & Chang, S. L. (2019). Meta-analysis of alcohol induced gut dysbiosis and the resulting behavioral impact. Behavioural brain research, 376, 112196. https://doi.org/10.1016/j.bbr.2019.112196

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