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Long-term dietary patterns are associated with pro-inflammatory and anti-inflammatory features of the gut microbiome
In this 2021 study, metagenomic sequencing was performed on patients with Crohn’s disease, ulcerative colitis, irritable bowel syndrome (IBS), and on the general population. The aim was to investigate the relationship between the gut microbiome profile and dietary factors among people with and without gastrointestinal problems. A total of 38 associations between dietary patterns and microbial clusters were found. Sixty-one individual foods and nutrients were also linked with 61 microbial species among healthy individuals and patients with IBS, Crohn’s disease, and ulcerative colitis. Processed foods and animal-derived foods were repeatedly related to large populations of Firmicutes (Ruminococcus species). Conversely, there was a connection between fish and plant foods, and higher abundance of certain commensals (organisms that receive benefits from other organisms without harming or helping it). This study identified dietary patterns that consistently correlate with groups of bacteria with shared functional roles in both health and disease. Furthermore, the results indicated a correlation between specific foods and nutrients with species known to infer mucosal protection and anti-inflammatory effects. [NPID: GI problems, IBS, irritable bowel syndrome, Crohn’s, Crohn’s disease, ulcerative colitis, colitis, diet, dietary patterns, microbes, microbiome, gut, gut microbes, gut microbiome, anti-inflammatory, inflammation, fish, plants]
Year: 2021
