Ketogenic diet prevents impaired prepulse inhibition of startle in an acute NMDA receptor hypofunction model of schizophrenia

The ‘leaky gut hypothesis’ proposes that increasing intestinal permeability may contribute to the association between inflammation with major depressive disorder (MDD) and suicidal behavior. This 2019 study thus evaluated patients with a recent suicide attempt (rSA), MDD subjects with no history of a suicide attempt (nsMDD), and healthy controls (HC) on their plasma gut permeability […]

This 2020 review discusses the roles of dietary factors in the risk and symptomatology of major depressive disorder (MDD). Despite being somewhat overlooked, dietary factors represent a highly promising approach towards finding new antidepressant pathways. Patients with mental disorders are deficient in various groups of nutrients such as vitamins. Also, people with major depressive disorder […]