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Inflammatory potential of diet is associated with biomarkers levels of inflammation and cognitive function among postmenopausal women
The purpose of this 2018 study was to assess whether the cognitive function of postmenopausal women is affected by the inflammatory potential of their diet or their circulating level of inflammatory biomarkers. The biochemical inflammatory biomarkers analyzed in this trial include c-reactive protein (CRP), interleukin-6 (IL-6), and tumor necrosis factor alpha (TNF-α). The 222 postmenopausal women in Korea were assessed on the inflammatory potential of their diets through a dietary inflammatory index. Those participants with an inflammatory diet showed significantly higher cognitive function (indicated by the Mini-Mental State Examination) than those with the most pro-inflammatory diets. These women with inflammatory diets also had significantly lower BMI, TNF-α concentrations, and percentage fat mass, compared with postmenopausal women with the most pro-inflammatory diets. Moreover, the authors discovered that women with cognitive impairment had substantially higher IL-6 concentrations, were less educated, and less physically active, compared with cognitively “normal” women. Women with the most proinflammatory diets were more likely to have cognitive damage compared to those with the most anti-inflammatory diets, even after adjustments were made in the analysis models. To conclude, dietary inflammation may increase the risk of cognitive dysfunction among postmenopausal women. Following an anti-inflammatory dietary pattern may help prevent cognitive decline. [NPID: cognition, cognitive impairment, inflammation, diet, inflammatory diets, postmenopause, menopause, Korea, inflammatory diet]
Year: 2018
