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I “Gut” rhythm: the microbiota as a modulator of the stress response and circadian rhythms
Modern habits are increasingly disrupting our health. With our lives often marked by circadian disruption and stress, it is crucial to understand how we respond to these external factors and how we can target their mediators to promote better health. More and more research emphasizes how the gut microbiome affects behavior and brain function. It is well recognized that the gut microbiota influences the stress response and circadian rhythms, crucial for adjusting to environmental changes. Research has demonstrated that gut microorganisms may affect circadian rhythms and alter the body’s reaction to stress. While research has established strong connections between the gut microbiota, circadian rhythms, and stress responses, these studies were largely conducted separately, making it difficult to understand how these factors interact fully. This review by Tofani, Clarke & Cryan examines how the gut microbiota may control the integration of stress responses and circadian rhythms in animals and its effects on brain health and illness, given the interdependence of these signals. [NPID: Circadian rhythm, gut microbiota, microbiota‐gut–brain axis, stress response]
Year: 2025
