Gutted! Unraveling the role of the microbiome in major depressive disorder

This 2021 article reviews the currently available evidence on the role of psychobiotics in reducing depression-related outcomes, bringing attention to the gaps in knowledge and challenges involved in this area of research. Psychobiotics are believed to potentially modulate the bidirectional communication between the gastrointestinal tract and the central nervous system. While causality has yet to […]

Changes in gut-brain communication and the gut microbiota ecosystem due to early life stress are critical factors in the development of stress-related disorders. However, Wilmes et al. (2024) highlight that the specific ways in which early life stress alters the gut microbiota and its role in sex-specific susceptibility to various gut-brain phenotypes in adulthood remain […]